![]() ![]() Here, we report that Epsin 3 (EPN3) is an oncogene with prognostic and therapeutic relevance in breast cancer. However, there is scarce evidence for genetic alterations of endocytic proteins as causative in high incidence human cancers. The subversion of endocytic routes leads to malignant transformation and has been implicated in human cancers. Nature Communications volume 11, Article number: 3020 ( 2020) A self-sustaining endocytic-based loop promotes breast cancer plasticity leading to aggressiveness and pro-metastatic behavior ![]()
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